Scleromyositis: A Novel Entity Beyond Systemic Sclerosis and Autoimmune Myositis

Autoimmune hepatitis and systemic sclerosis: a new overlap syndrome?

OBJECTIVE We report the cases of two patients with the complete CREST variant (calcinosis, Raynaud's phenomenon, oesophageal dysmotility, sclerodactyly, telangiectasia) of systemic sclerosis (SSc) who developed autoimmune hepatitis. RESULTS Our findings suggest that autoimmune hepatitis can be considered to be one of the liver manifestations associated with SSc. Our data also indicate that, b...

A Novel Genetic Association With Systemic Sclerosis: The Utility of Whole-Exome Sequencing in Autoimmune Disease.

Contracturing granulomatous myositis: a separate entity.

Granulomatous muscle disease is most commonly seen in sarcoidosis, but may be seen in association with a wide variety of other disorders or in isolation. Patients with granulomatous myositis usually present with slowly progressive muscle pain and weakness affecting mainly proximal muscles. There are, however, a few reports of granulomatous muscle disease presenting with flexion contractures of ...

Tropical myositis: an underdiagnosed entity?

Tropical myositis is a condition characterised by the presence of suppurative lesions within skeletal muscles. There has been little agreement regarding the terminology various names used include purulent tropical myositis, tropical pyornyositis, tropical skeletal muscle abscess, spontaneous bacterial myositis or epidemic abscess. The earliest anecdotal reports of patients presenting both skele...

Atorvastatin-induced necrotizing autoimmune myositis

The general aim of this study was to evaluate the disease spectrum in patients presenting with a pure polymyositis (pPM) phenotype. Specific objectives were to characterize clinical features, autoantibodies (aAbs), and membrane attack complex (MAC) in muscle biopsies of patients with treatment-responsive, statin-exposed necrotizing autoimmune myositis (NAM). Patients from the Centre hospitalier...